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These medications mimic the action of the glucagon-like peptide-1 hormone, stimulating insulin release, inhibiting glucagon secretion, and delaying gastric emptying, said Jeffrey Joseph, MD, an oculofacial plastic surgeon in private practice in Newport Beach, California

They're offered in several brand name forms, like Ozempic, where semaglutide is the main substance, or Zepbound, where tirzepatide is the main substance

Semaglutide, a type of GLP-1R agonists with 94% sequence homology to GLP-1 and with an extended half-life of approximately 1 week, has been clinically approved to treat T2DM and is available in subcutaneous and oral dosage form (136, 137)

About a quarter of patients had a blood pressure drug trimmed or dropped during the study, the move a doctor makes when a reading runs low