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At the same time, PDL1 nanoparticle treatment combined with the activation of the photosensitizer indocyanine green triggered by NIR laser irradiation can induce the production of reactive oxygen species thereby promoting CTLs infiltration into tumors and sensitizing tumors to PD-L1 blockade therapy and effectively inhibiting tumor growth and metastasis (180)

L-Carnitine is a conditionally essential amino acid derivative that plays a foundational and non-negotiable role in cellular bioenergetics and lipid metabolism