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Realistic Month-by-Month Expectations Based on trial data, here's what someone starting at 240 lbs (109 kg) might expect on the 12mg dose trajectory: Month 1 (2mg): 5-7 lbs lost

A separate analysis in Nature Medicine found that retatrutide produced significant reductions in liver fat content in participants with metabolic dysfunction-associated steatotic liver disease (MASLD), suggesting benefits beyond simple weight reduction

Participants will either get insulin icodec that participants will have to inject once a week on the same day of the week, or insulin degludec that participants will have to inject once a day at the same time every day

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