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A proof of the dynamic balancing of carnitine homeostasis derives from the observation that, under regular diet, patients carrying defects of the carnitine biosynthesis enzymes, do not apparently display carnitine deficiency, because the reduced synthesis is compensated by carnitine dietary intake and increased renal reabsorption (Stanley et al., 1992

36 The majority of malignant ovarian tumors originate in epithelial cells

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In addition, analysis of p53-induced apoptosis in a human colon cancer cell line showed that elevated p53 expression was associated with an elevation of GPx1 [31, 32]