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Nishida Y, Ishizawa J, Ruvolo VR, Wang F, Takahashi K, Mak PY, Carter B, Andreeff M

N Engl J Med 2021;384:1113-24.ArticlePubMed 110

Emergency Planning and Backup Strategies Despite meticulous planning, travel emergencies happen

Cycle Guidelines Approach Standard Duration 4-6 weeks Review point Week 4 Best for General research planning Approach Extended Duration 6-8 weeks Review point Week 6 Best for Stubborn-injury research models Approach Long Duration 8-12 weeks Review point Week 8 Best for Slow-remodeling tissue research planning Off periods of 2-4 weeks between cycles are common in research planning