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32.Yang, Y., Li, T., Li, Z., Liu, N., Yan, Y., et al

If not improving, contact your healthcare provider about potential dose adjustment or extended hold at current level

A 2025 meta-analysis of randomized controlled trials found significant blood pressure effects (PMID: 41000008), and a separate meta-analysis focused on individuals with insulin resistance and chronic diseases found similar patterns (PMID: 28724644)