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None of the following should be read as encouragement to self-administer

If GHK-Cu penetrates poorly through intact skin, the observed clinical effects could be occurring primarily at the epidermal level rather than reaching dermal fibroblasts where collagen synthesis occurs

Co-immunoprecipitation studies demonstrated that the peptide reduces eNOS/caveolin-1 binding by approximately 50%, effectively doubling the available eNOS for nitric oxide production

Because the peptide originates in gastric juice and much of the preclinical research examined gut lining integrity, the oral route puts it directly where that research focused