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It has the ability to scavenge free radicals, provide hydrogen and electrons, exhibit reductive activity, and act as a chelating agent for metal ions ( Studies have demonstrated that red wine possesses antioxidant properties, enhancing the serums antioxidant capacity and safeguarding cell structure against peroxidation-induced damage
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Berberine inhibits the nuclear translocation of -catenin and the expression of target genes such as cyclin D1 and VEGF by downregulating Trx1, and simultaneously inhibits MAPK1 (ERK1/2) phosphorylation and NOX4-mediated ROS production, thereby blocking the metabolic reprogramming of abnormal PASMC proliferation (Yu et al., 2020
Injectable peptides require more handling care than oral supplements but deliver superior bioavailability
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