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Description

A recent analysis of the World Health Organizations pharmacovigilance database, VigiBase, found that there was an increased risk of suicidal ideation for patients taking semaglutide, liraglutide, and tirzepatide (Mounjaro, Zepbound) as compared with other medications for diabetes

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This work was supported by the National Institute of Diabetes, Digestive and Kidney Diseases R00DK1208689 and P30DK045735 grants, the National Institute of Health Yale-Murine Tissue Mapping Center Grant U54 AG079759 and the National Institute of Health National Institutes of Aging Grant P30AG066508

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Furthermore, the anti-inflammatory effects of these drugs may contribute to their potential neuroprotective benefits against mood disorders

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