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Limit exposure to endocrine-disrupting chemicals (EDCs): While more research is still needed, there is evidence that suggests that exposure to certain types of chemicals (including phthalates and parabens, found in many consumer goods) is linked to worsening of some symptoms of menopause, including hot flashes [19]

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Leukemia 15:16331640 Ishii T, Bannai S, Sugita Y (1981) Mechanism of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro

Yes, regular monitoring is essential and should include weight, nutritional status, blood pressure, heart rate, mental health, and tolerability of side effects