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TRIUMPH-1 reported mean body weight reduction of 19.0%, 25.9%, and 28.3% on the 4 mg, 9 mg, and 12 mg arms respectively over 80 weeks

Patients can try taking their medication with food or starting with a lower dose and gradually increasing it at the discretion of their prescriber

Schedule prompt medical evaluation (within 24-48 hours) for: Gradually worsening shortness of breath over days to weeks Dyspnea with exertion that is new or significantly worse than baseline Breathing difficulty accompanied by persistent cough or fever Leg swelling, weight gain, or orthopnea (difficulty breathing when lying flat) Respiratory symptoms associated with severe ongoing nausea, vomiting, or inability to maintain hydration Patients should not discontinue GLP-1 medications without medical guidance (except in cases of suspected severe allergic reactions), but should contact their healthcare provider promptly to discuss respiratory symptoms

GLP-1: What These Medications Mean for Both Men and Women GLP-1 medications have quickly become one of the most talked-about health tools of our time and for good reason