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Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine
Journal of Cosmetic Dermatology, 20 (12), 3759-3781
OU749, a species-specific uncompetitive GGT inhibitor, exhibits low toxicity and a broad therapeutic window for humans
A new study found that GLP-1 reduces heavy drinking days in treatment seeking people with alcohol use disorder and obesity: spkl.io/6012AfU04 Alcohol use disorder accounts for 5% of deaths worldwide annually, and there is an urgent need for new treatments
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