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This rise in LH and FSH drives gamete maturation: follicle development and ovulation in people with ovaries and spermatogenesis support in people with testes

The recognition of HBV by these receptors activates downstream signaling pathways, including the NF-B and JAK-STAT pathways

In terms of R&D progress, Lilly achieved several key milestones in the GLP-1 field in the first 9 months, such as the successful completion of six Phase III studies for the small molecule GLP-1R agonist orforglipron (three of which were completed in Q3), while the Phase III study of tirzepatide (Mounjaro) for paediatric and adolescent type 2 diabetes (T2D) met its primary endpoint