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The one human trial that will measure tolerability directly has not started reporting it is only recruiting (planned 2026), studies a topical gel on small standardized wounds , and lists safety as a secondary, not primary, outcome (NCT07437586)

Most men receive a dosage of 1,000 to 4,000 units of hCG injected into a muscle two to three times a week for several weeks or months

doi: 10.1182/BLOODADVANCES.2019001143

Chemical Peels For Pigmentation : There are medically-approved chemical peels of varying strengths to address different types of pigmentation by getting rid of the damaged layers and promoting skin renewal