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471 Knocking down FTH in cardiomyocytes prevents free iron from being stored in ferritin, increases unstable iron pools, promotes intracellular ROS production, activates oxidative stress, and causes ferroptosis in cardiomyocytes, leading to age-related heart damage

Kwanten WJ, Vandewynckel YP, Martinet W, De Winter BY, Michielsen PP, Van Hoof VO, Driessen A, Timmermans JP, Bedossa P, Van VH, Francque SM (2016) Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice

GHK-Cu, also known as copper tripeptide-1, directly stimulates collagen and elastin production at the cellular level

What it does not justify is casual, unsupervised use of a compound whose long-term human safety profile is still being written