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Many individuals require a higher dose titration than what they initially begin with, or are currently taking, to truly unlock the medication's full potential for weight loss

When tirzepatide activates GLP-1 receptors, it stimulates glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite through central pathways in the hypothalamus

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Studies show GLP-1s help decrease weight, improve metabolic complications, lower flares and stiffness, and may slow joint damage when combined with DMARDs or biologics