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J Bone Miner.Res 2005;20(7):1125-1135

To determine if GLP-1R induces cAMP generation specifically at VAPB locations, we modified a fluorescence resonance energy transfer (FRET)-based system of biosensors targeted to endogenous proteins (FluoSTEPs) 25 , so that a FRET cAMP sensor would fully reconstitute only in the presence of the GFP 11 fragment fused to VAPB, resulting in functional biosensor assembly specifically at VAPB loci (Supplementary Fig

And then this class of diabetes drugs, and sort of tellingly, it's these huge companies in diabetes, Eli Lilly and Novo Nordisk, which have worked in insulin for almost a century, that brought these drugs to the market for obesity

2023;15:e46623