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Contrave delivered roughly 5-8% body weight reduction over 56 weeks across COR clinical trials

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13,37 However, acquired nevi (banal or atypical) themselves have minimal malignant potential, with the lifetime risk of a particular nevus transforming into melanoma estimated to be about 1 in 10,000, 38 and most cutaneous melanomas arise de novo (not in association with a nevus)