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Secrecin de glucagn: En pacientes con diabetes mellitus tipo 2, semaglutida result en las siguientes reducciones relativas en el glucagn en comparacin con el placebo: glucagn en ayuno (821%), respuesta de glucagn posprandial (1415%) y media de concentracin de glucagn de 24 horas (12%)

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The American Diabetes Association (ADA) Standards of Care support considering GLP-1 receptor agonists, including dual agonists like tirzepatide, early in the treatment algorithm for type 2 diabetes, especially in patients with established cardiovascular disease, chronic kidney disease, or those requiring significant weight reduction