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Vasan RS, Sullivan LM, DAgostino RB, Roubenoff R, Harris T, Sawyer DB, Levy D, Wilson PW: Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study

3,16 N -Acetylglutamate synthetase (NAGS) deficiency NAGS deficiency is an autosomal-recessive disorder

Supplementing with it during a CJC1295 cycle can help maintain optimal hormone balance, especially in older adults or those with lower natural androgen production

Of note, treatment with the neutralizing IGF-IR monoclonal antibody is incapable of overcoming resistance to hormone deprivation or antiestrogen therapy, due to the compensation by InsR [107]