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However, dietary carbohydrates encompass not only monosaccharides (e.g., glucose, fructose) and disaccharides (e.g., sucrose, lactose) but also polysaccharides and added sugars (artificial sweeteners) (112)
Aberrant and diseased astrocytes promote death of motor neurones in amyotrophic lateral sclerosis, whereas loss of astrocyte homoeostatic support contributes to neuronal malfunction and demise in AD, PD, and HD
Analogous pharmacotherapeutic studies in humans and Lurcher mice allowing direct comparison of the effects are lacking
PMCID: PMC11091273 Morsali S, Sabahi Z, Kakaei J, Hakimzadeh Z, Hamidi S, Gholipour-Khalili E, Sanaie S, Talebi M, Naseri A (2023) Clinical efficacy and safety of melatonin supplementation in multiple sclerosis: a systematic review
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