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The treatment is regarded as relatively safe, but like any medicine, has potential side effects: Diarrhoea Dizziness Headache Hot flush Nausea Skin reactions Urine discolouration If you are allergic to cobalt please notify your clinician (1-3% of the population have this allergy)

The implications extend well beyond weight-loss drugs: as more high-demand therapies emerge, similar workarounds are likely to appear wherever conventional healthcare systems struggle to keep pace

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May 2003;8(2):106-28