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Having targeted Hims & Hers last year, the FDA has issued warnings to more telehealth companies over their promotion of GLP-1 drugs used to treat diabetes and obesity

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The ravagalimab Phase 2 single-arm study evaluated this anti-CD40 monoclonal antibody in moderate to severe UC patients by constructing synthetic placebo control groups using two approaches: first, a Bayesian method incorporating historical placebo data from meta-analyses of tofacitinib, ustekinumab, and upadacitinib pivotal trials, taking advantage of objective centrally-read endoscopies and low placebo endoscopic improvement rates