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[PubMed Central ID: PMC9597294]

Beyond its hypnotic effect, the DSIP DSIP exhibits documented pleiotropic properties: analgesic action via modulation of endogenous opioid pathways, anti-stress effects through the reduction of cortisol and ACTH, antioxidant and neuroprotective properties, and modulation of tolerance to ethanol and addictive substances

BACKGROUND [0002] Semaglutide has a chemical structure of Formula I: [0003] Semaglutide is a long-acting GLP-1 analog developed by Novo Nordisk, which only requires subcutaneous injection once a week and is still in clinical phase III currently