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Most of the inhibitors with renal protection effects target HDAC1-11 and mediate related pathways to play a renal protection role

Moreover, 5-FU treatment decreased the viability of the GST 4QN -p53-expressing cells compared to the GST WT -p53-expressing cells (Fig

This was together with the proposal that the function of this cycle was to protect redox-sensitive proteins from uncontrolled oxidation by reactive oxygen species (ROS), particularly hydrogen peroxide (H 2 O 2 )