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If the stores are exhausted, the reactive NAPQI remains in the liver, where it can begin to cause cellular stress

Genetic Factors That Influence GLP-1 Response and Hormone Sensitivity Your genetic makeup influences how sensitively your body responds to GLP-1 drugs and how strongly hormonal shifts affect your appetite control

Patients with already-marginal thyroid function are particularly vulnerable, and the symptoms (fatigue, cold intolerance, hair shedding, the plateau itself) often look exactly like the patient is just "not trying hard enough." Sex hormone status

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