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The 124,001 participants without a history of substance abuse who were taking GLP-1 drugs had 14% lower odds of developing a new substance use disorder over the following three years than the 400,816 similar patients prescribed SGLT-2 inhibitors

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Slowing of gastric motility was expected to increase solubility and therefore potentially drug absorption

By stabilizing sarcolemmal ion flux and atrioventricularnodal conduction, magnesium elevates the threshold for early afterdepolarizations, playing a potential role in controlling torsades de pointes and atrial fibrillation triggers ( Endothelial Function