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The reductions were dose-dependent: 4.9% with the 0.5mg dose, 15.2% with 4mg, 26.1% with 8mg, and 23.2% with 12mg

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[1] [2] As of 20242025, retatrutide remains under clinical investigation and has not been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the United Kingdom, nor by the European Medicines Agency (EMA) or the US Food and Drug Administration (FDA) for routine clinical use