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In serum-free or serum-reduced culture media, cells may secrete binding proteins that dampen native IGF-1 activity, producing inconsistent stimulation

Platinum (II) class antitumor drugs such as cisplatin and oxaliplatin, widely used in cancer chemotherapy, target DNA damage and overall cytotoxicity in tumor cells, resulting in cell death (135)

Fragments, with their small molecular size, achieve a more efficient chemical space exploration than larger and potentially more potent molecules used in HTS ( Fig

Formulation of quaternized aminated chitosan nanoparticles for efficient encapsulation and slow release of curcumin