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Additionally, the positive outcomes of ongoing trials SURPASS-CVOT and SURMOUNT-MMO will provide definitive evidence regarding the cardiovascular safety and efficacy of tirzepatide compared to dulaglutide and reduction in morbiditiy and mortality in adults with obesity respectively

A Role of PLC/PKC-Dependent Pathway in GLP-1-Stimulated Insulin Secretion

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Some are also approved for chronic weight management in individuals with overweight and at least one weight-related condition