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Association of Piriformospora indica with Arabidopsis thaliana roots represents a novel system to study beneficial plant-microbe interactions and involves early plant protein modifications in the endoplasmic reticulum and at the plasma membrane

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Its primary mechanisms of action center on tissue regeneration, anti-inflammatory signaling, and angiogenesis the formation of new blood vessels

The subunit composition of glutamate receptors and their localization in oligodendrocytes (soma, processes, myelin) predispose them to the susceptibility to ischemic injury as their AMPA receptors are especially permeable to Ca 2+ (Kradttir and Attwell, 2007) and their NMDA receptors are only weakly blocked by Mg 2+ , allowing them to produce considerable currents at resting membrane potential (Kradttir et al., 2005)