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This binding enhances the activity of GTPase Drp1, resulting in mitochondrial fusion and fission imbalances, mitochondrial distribution abnormalities, and mitochondrial axonal transport defects

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On the other hand, ferroptosis can directly impair the antitumor immune response by negatively affecting key immune cells, including natural killer (NK) cells, B cells, cytotoxic T cells, and antigen-presenting cells (APCs), which are critical components of antitumor immune defense

However, some individuals may experience mild side effects such as pain or redness at the injection site