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However, overall mortality was not affected by extent of tumor resection or the addition of radiation therapy as an adjuvant, highlighting the need for continued efforts toward the development of effective treatment options to improve survival in patients with melanotic schwannomas

J Experimental Clin Cancer Res

IR may be responsible for high blood pressure via direct stimulation of reninangiotensinaldosterone system (Nickenig et al., 1998), activation of sympathetic system (Sowers et al., 2001) and downregulation of the natriuretic peptide system (Sarzani et al., 1999)