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Oral administration of MK-677 at 4 mg/kg significantly increased GH concentrations with a 1.8-fold increase in peak GH concentration (45.7 ng/mL), whereas administration of distilled water did not increase GH concentrations

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Laboratory research demonstrates efficacy in bleomycin-induced pulmonary fibrosis mouse models, with treated groups showing milder pathologic changes and less collagen deposition compared to controls