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A total of 12 events were reported in five participants (35.7%) in the normal hepatic function group, three events in three participants (42.9%) in the mild hepatic impairment group and one event in one participant (14.3%) in the moderate hepatic impairment group
Of these, pyridoxal 5'-phosphate (PLP) is the most metabolically active form and acts as an enzyme cofactor in the biochemical metabolism of amino acids
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