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Dapagliflozin Initial Combination Therapy With Metformin HCl Extended-Release A total of 1236 treatment-naive adult patients with inadequately controlled type 2 diabetes mellitus (HbA1c 7.5% and 12%) participated in 2 active-controlled trials of 24-week duration to evaluate initial therapy with dapagliflozin 5 mg (NCT00643851) or 10 mg (NCT00859898) in combination with metformin extended-release formulation

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As the prostate gland grows, it presses on the urethrathe tube that carries urine from the bladder and out of the body

It also demonstrated improvements in all prespecified cardiometabolic parameters