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All of these therapies can be helpful in healing
The production of significant lactate by tumor cells is due to glycolysis, which serves as an intermediary between tumor cells and TAMs, thereby enhancing M2-like polarization through hypoxia-inducible factor 1 (HIF1) [64]
Expert Opinion Management Approach Treatment decisions should typically be made after shared decision-making, with the patient informed of the risks, potential benefits, and alternatives
Cost and Accessibility Concerns The financial burden of B12 injections can be significant, especially when multiple doses are required
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