In both mice and humans, GH deficiency or GH insensitivity (Laron's syndrome caused by inactivating mutations of the GH receptor gene) minimally affect birth size, but lead to reduced growth during childhood and adolescence resulting in diminished stature (Savage et al ., 1993
A study presented at the Endocrine Society annual meeting examined 130 participants on semaglutide, comparing outcomes between a high-protein group (1.6 grams per kilogram of body weight daily, roughly 30% of total calories) and a standard-protein group (0.8 g/kg, roughly 15% of total calories)
For other tirzepatide side effects that people commonly worry about, like GI symptoms or body discomfort, this article on Zepbound and sulfur burps and this guide on Mounjaro and body aches cover those in more detail
Early analysis suggests that more than a third of users are new to the drugs, according to Truveta, a healthcare data company