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Redness, pain at the site of the injection Rare reactions include redness, transient muscle atrophy, polyarthralgia, hand swelling and rashes

Zhao L, Zhao Y, Liu R, Zheng X, Zhang M, Guo H, Zhang H, Ren F (2017) The transcription factor DAF-16 is essential for increased longevity in C

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Clearly, mouse joints and human osteoarthritis are not the same, and findings like these are best understood as early mechanistic evidence rather than clinical proof