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I started month 1 tirzepatide and have lost 10 lbs

Excessive shortening triggers persistent DNA damage response or genomic instability, causing cellular senescence, and is also strongly linked to lifespan (Whittemore et al., 2019

Surface markers and transendothelial migration of dendritic cells from elderly subjects

Furthermore, interactions between SFN and Glutathione S-Transferase P1 (GSTP1) gene variants have been observed, where SFN can modulate the expression levels of different GSTP1 haplotypes (54)