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It is an essential cofactor for many enzymes which require thiol-reducing equivalents, and helps to keep redox-sensitive active sites on enzymes in the necessary reduced state

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doi: 10.1038/d41586-024-02352-2

Following more than twenty years of advancement, RNA therapeutics has materialized as a clinical reality, with enhancements in the design and chemistry of siRNAs, ASOs, and mRNAs attaining adequate stability, immune evasion, and therapeutic efficacy, while delivery technologies have progressed through effective, biocompatible materials and high-throughput screening