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However, the course of treatment should be at least 6 months to obtain good results, which may have side effects, including skin atrophy, telangiectasia (spider vein, dilation of blood vessels), and acneiform eruptions (in this case, it is advisable to switch to topical immunomodulators)

In general, these clinical combination studies have focused on a limited number of cancer types, those including high-dose VitC mainly concerning pancreatic cancer, and lower pharmacological doses mainly concerning non-solid tumors (Fig

Laser Doppler Flowmetry Gingival blood flow (GBF) was measured by laser doppler flowmetry (LDF, Oxford Optronix Ltd, Oxford, UK) working at 780 nm