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In the Phase 3 TRIUMPH-4 trial (68 weeks), retatrutide demonstrated unprecedented weight loss in adults with obesity and knee osteoarthritis, with participants on the highest dose (12 mg) achieving an average weight loss of 28.7% (approximately 71 lbs)

Moreover, disconcertingly, individuals are often afflicted by NAFLD at a young age, signifying an extended time frame for the development of severe complications, including cancer and CVD (Reference Wai-Sun Wong, Ekstedt and Lai-Hung Wong1)

The pain in the carpal tunnel is caused by excess pressure that is put on the wrist and the median nerve

In the case of GLP-1s, that decision is a long-term commitment