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These individual unimolecular multi-agonists activities seemed to harmonize the overall metabolic efficacy, which predominantly results from synergistic glucagon action to increase energy expenditure, GLP-1 action to reduce caloric intake and improve glucose control, and GIP action to potentiate the incretin effect and buffer against the diabetogenic effect of inherent glucagon activity

The Journal of Physiology , 589 , 963-973

Unlike L-carnitine, which does not contain an acetyl group, ALCAR can support acetylcholine synthesis, because the acetyl group in ALCAR can be delivered to coenzyme A to yield acetyl-CoA, which in turn can be used for the synthesis of the neurotransmitter acetylcholine