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The evidence from published intervention trials is consistent: T/T individuals receiving adequate 5-MTHF + B12 + B6 supplementation normalize plasma homocysteine to levels similar to C/C individuals, restore BH4 availability and endothelial function, and reduce the functional consequences of MTHFR impairment across most of the five longevity mechanisms described above

Pharmaceutical manufacturers provide doctors and clinics with free samples of their medications to help patients get started on treatment

Presented at #ECO2025: In the SURMOUNT-5 phase 3b trial involving adults with obesity without type 2 diabetes, tirzepatide was superior to semaglutide in reducing body weight and waist circumference

Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: A randomized, placebo-controlled and active comparator-controlled phase 2 trial