The release of neurotransmitters, specifically glutamate, into the extracellular compartment results in an overstimulation of glutamate receptors linked to ion channels and creates prolonged membrane depolarization, depletion of ATP stores, and an increase in intracellular calcium derived from both extracellular and intracellular stores, indicating disturbances in mitochondrial function
Researchers are still studying the long-term effects of these medications and how long patients should take them
If you're thinking about starting these medications, it's a good idea to talk to your healthcare provider or pharmacist about costs and any available financial assistance programs
While the original intent for GLP-1 medications was for diabetes care, its efficacy as a weight management drug means that researchers like Colleen Tewksbury, assistant professor in nutrition science, are looking closely at how people take it as a treatment for overweight and obesityfor instance, the medications impact on micronutrient deficiencies resulting from weight loss