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Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131

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Madsen K, et al

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Semaglutide works by slowing stomach emptying and activating GLP-1 receptors in your brain, which reduces hunger and increases fullness signals

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Monoclonal CHO-K1 cells stably expressing human SNAP-GLP-1R (CHO-K1-SNAP-GLP-1R) were generated by G418 selection, with single clones obtained by FACS and subsequently expanded

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