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The researchers could not conduct sex-stratified analyses of the previous prescription group because of its smaller sample size

Notably, the data set lacked information on ethnicity, which is particularly significant given that previous research indicates African American race was associated with 33% higher rates of OSA

Compare this to the indefinite treatment paradigm of pharmaceutical GLP-1 medications, where the expectation is continuous use and discontinuation typically leads to rebound

Starting with a murine ileum explant model, the authors showed that intraluminal LPS could stimulate GLP-1 secretion and that GLP-1 secretion was rapidly increased after direct LPS stimulation of an EEC cell line (STC-1 cells)