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The semaglutide-induced fatigue stems from caloric deficit, blood sugar fluctuations, and metabolic recalibration, not from B12 deficiency

When extracellular thiamine concentrations are below 2 mmol/L, active transport via THTR2 is possible

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Kybella, containing synthetic deoxycholic acid (DCA), directly causes adipocytolysis by rupturing fat cell membranes, leading to fat cell death