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Of importance, a current phase II clinical trial NCT03872427 is analyzing the therapeutic response of the advanced solid tumors to CB-839/telaglenastat depending on the mutations in genes regulating the antioxidant system such as neurofibromatosis-1 gene (NF1), Kelch-like ECH-associated protein 1 KEAP1, nuclear factor erythroid 2-related factor 2 (NRF2), and serine/threonine kinase 11 (STK11)

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Freezing reconstituted GHK-Cu isn't ideal because ice crystal formation can damage peptide structure